EIF3B Antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP86851-P050-25UL
100 ul
£412.00
ARP86851-P050-100UL
About this Product
- SKU:
- ARP86851-P050
- Additional Names:
- PRT1; EIF3S9; EIF3-ETA; EIF3-P110; EIF3-P116
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex; which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1; eIF-1A; eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation; including cell cycling; differentiation and apoptosis; and uses different modes of RNA stem-loop binding to exert either translational activation or repression.(Microbial infection) In case of FCV infection; plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2.
- Gene Details:
- eukaryotic translation initiation factor 3 subunit B
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human EIF3B
- Molecular Weight:
- 96 kDa
- Protein Details:
- Eukaryotic translation initiation factor 3 subunit B
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
