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Antibodies

ARVCF Antibody - middle region

Product Sizes
25ul
£177.00
ARP84952-P050-25UL
100 ul
£412.00
ARP84952-P050-100UL
About this Product
SKU:
ARP84952-P050
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Armadillo Repeat gene deleted in Velo-Cardio-Facial syndrome (ARVCF) is a member of the catenin family. This family plays an important role in the formation of adherens junction complexes; which are thought to facilitate communication between the inside and outside environments of a cell. The ARVCF gene was isolated in the search for the genetic defect responsible for the autosomal dominant Velo-Cardio-Facial syndrome (VCFS); a relatively common human disorder with phenotypic features including cleft palate; conotruncal heart defects and facial dysmorphology. The ARVCF gene encodes a protein containing two motifs; a coiled coil domain in the N-terminus and a 10 armadillo repeat sequence in the midregion. Since these sequences can facilitate protein-protein interactions ARVCF is thought to function in a protein complex. In addition; ARVCF contains a predicted nuclear-targeting sequence suggesting that it may have a function as a nuclear protein.
Gene Details:
armadillo repeat gene deleted in velocardiofacial syndrome
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human ARVCF
Molecular Weight:
98 kDa
Protein Details:
armadillo repeat protein deleted in velo-cardio-facial syndrome
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody