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Antibodies

Anti-ITM2B

Product Sizes
25ul
£177.00
ARP84613-P050-25UL
100 ul
£412.00
ARP84613-P050-100UL
About this Product
SKU:
ARP84613-P050
Additional Names:
BRI; FBD; ABRI; BRI2; E25B; E3-16; RDGCA; imBRI2; BRICD2B
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein; thereby increasing the size of the secreted peptide; are associated with two neurogenerative diseases; familial British dementia and familial Danish dementia.
Gene Details:
integral membrane protein 2B
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human ITM2B
Molecular Weight:
29 kDa
Protein Details:
integral membrane protein 2B
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody