MAP2K3 Antibody
Product Sizes
25ul
£177.00
ARP84407-P050-25UL
100 ul
£412.00
ARP84407-P050-100UL
About this Product
- SKU:
- ARP84407-P050
- Additional Names:
- MEK3; MKK3; MAPKK3; PRKMK3; SAPKK2; SAPKK-2
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress; and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin; and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase; which thus leads to the constitutive activation of MAPK14; and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.
- Gene Details:
- mitogen-activated protein kinase kinase 3
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human MAP2K3
- Molecular Weight:
- 36 kDa
- Protein Details:
- dual specificity mitogen-activated protein kinase kinase 3
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
