BAP1 Antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP84077-P050-25UL
100 ul
£412.00
ARP84077-P050-100UL
About this Product
- SKU:
- ARP84077-P050
- Additional Names:
- UCHL2; hucep-6; HUCEP-13
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition; the enzyme may be involved in regulation of transcription; regulation of cell cycle and growth; response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS); which involves increased risk of cancers including malignant mesothelioma; uveal melanoma and cutaneous melanoma.
- Gene Details:
- BRCA1 associated protein 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human BAP1
- Molecular Weight:
- 80 kDa
- Protein Details:
- ubiquitin carboxyl-terminal hydrolase BAP1
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
