KCNQ4 Antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP80989-P050-25UL
100 ul
£412.00
ARP80989-P050-100UL
About this Product
- SKU:
- ARP80989-P050
- Additional Names:
- DFNA2; KV7.4; DFNA2A
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene forms a potassium channel that is thought to play a critical role in the regulation of neuronal excitability; particularly in sensory cells of the cochlea. The current generated by this channel is inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine; a novel anti-convulsant drug. The encoded protein can form a homomultimeric potassium channel or possibly a heteromultimeric channel in association with the protein encoded by the KCNQ3 gene. Defects in this gene are a cause of nonsyndromic sensorineural deafness type 2 (DFNA2); an autosomal dominant form of progressive hearing loss. Two transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- potassium voltage-gated channel subfamily Q member 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human KCNQ4
- Molecular Weight:
- 76 kDa
- Protein Details:
- potassium voltage-gated channel subfamily KQT member 4
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
