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Antibodies

SEMA4D Antibody - middle region

Product Sizes
25ul
£177.00
ARP80973-P050-25UL
100 ul
£412.00
ARP80973-P050-100UL
About this Product
SKU:
ARP80973-P050
Additional Names:
A8; GR3; BB18; CD100; COLL4; SEMAJ; coll-4; C9orf164; M-sema-G
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2; which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA.
Gene Details:
semaphorin 4D
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human SEMA4D
Molecular Weight:
94 kDa
Protein Details:
semaphorin-4D
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody