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Antibodies

DUOX1 Antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP80953-P050-25UL
100 ul
£412.00
ARP80953-P050-100UL
About this Product
SKU:
ARP80953-P050
Additional Names:
LNOX1; THOX1; NOXEF1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter; thyroperoxidase; and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase; lactoperoxidase; and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Gene Details:
dual oxidase 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human DUOX1
Molecular Weight:
170 kDa
Protein Details:
dual oxidase 1
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody