IGF2R Antibody - middle region
Product Sizes
25ul
£177.00
ARP80628-P050-25UL
100 ul
£412.00
ARP80628-P050-100UL
About this Product
- SKU:
- ARP80628-P050
- Additional Names:
- MPR1; MPRI; CD222; CIMPR; M6P-R; MPR300; CI-M6PR; MPR 300; M6P/IGF2R
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes a receptor for both insulin-like growth factor 2 and mannose 6-phosphate. The binding sites for each ligand are located on different segments of the protein. This receptor has various functions; including in the intracellular trafficking of lysosomal enzymes; the activation of transforming growth factor beta; and the degradation of insulin-like growth factor 2. Mutation or loss of heterozygosity of this gene has been association with risk of hepatocellular carcinoma. The orthologous mouse gene is imprinted and shows exclusive expression from the maternal allele; however; imprinting of the human gene may be polymorphic; as only a minority of individuals showed biased expression from the maternal allele.
- Gene Details:
- insulin like growth factor 2 receptor
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human IGF2R
- Molecular Weight:
- 274 kDa
- Protein Details:
- cation-independent mannose-6-phosphate receptor
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
