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Antibodies

APC Antibody - middle region

Product Sizes
25ul
£177.00
ARP79570-P050-25UL
100 ul
£412.00
ARP79570-P050-100UL
About this Product
SKU:
ARP79570-P050
Additional Names:
GS; DP2; DP3; BTPS2; DESMD; DP2.5; PPP1R46
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion; transcriptional activation; and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP); an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Gene Details:
adenomatous polyposis coli
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human APC
Molecular Weight:
143 kDa
Protein Details:
adenomatous polyposis coli protein
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody