TYROBP Antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP79200-P050-25UL
100 ul
£412.00
ARP79200-P050-100UL
About this Product
- SKU:
- ARP79200-P050
- Additional Names:
- DAP12; KARAP; PLOSL; PLOSL1
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction; bone modeling; brain myelination; and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL); also known as Nasu-Hakola disease. Its putative receptor; triggering receptor expressed on myeloid cells 2 (TREM2); also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene
- Gene Details:
- TYRO protein tyrosine kinase binding protein
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C terminal region of human TYROBP
- Molecular Weight:
- 12 kDa
- Protein Details:
- TYRO protein tyrosine kinase-binding protein
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
