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Antibodies

Anti-GSTM4

Product Sizes
25ul
£177.00
ARP79120-P050-25UL
100 ul
£412.00
ARP79120-P050-100UL
About this Product
SKU:
ARP79120-P050
Additional Names:
GTM4; GSTM4-4
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present; eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha; kappa; mu; omega; pi; sigma; theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds; including carcinogens; therapeutic drugs; environmental toxins and products of oxidative stress; by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains; as well as in tissue expression patterns; to accommodate an increasing number of foreign compounds. Multiple transcript variants; each encoding a distinct protein isoform; have been identified. [provided by RefSeq; Jul 2008]
Gene Details:
glutathione S-transferase mu 4
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human GSTM4
Molecular Weight:
26 kDa
Protein Details:
glutathione S-transferase Mu 4
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody