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Antibodies

BRAF Antibody - middle region

Product Sizes
25ul
£177.00
ARP78862-P050-25UL
100 ul
£412.00
ARP78862-P050-100UL
About this Product
SKU:
ARP78862-P050
Additional Names:
NS7; B-raf; BRAF1; RAFB1; B-RAF1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway; which affects cell division; differentiation; and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome; a disease characterized by heart defects; mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers; including non-Hodgkin lymphoma; colorectal cancer; malignant melanoma; thyroid carcinoma; non-small cell lung carcinoma; and adenocarcinoma of lung. A pseudogene; which is located on chromosome X; has been identified for this gene.
Gene Details:
B-Raf proto-oncogene; serine/threonine kinase
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human BRAF
Molecular Weight:
84 kDa
Protein Details:
serine/threonine-protein kinase B-raf
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody