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Antibodies

NRXN1 Antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP78173-P050-25UL
100 ul
£412.00
ARP78173-P050-100UL
About this Product
SKU:
ARP78173-P050
Additional Names:
PTHSL2; SCZD17; Hs.22998
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission; and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3;000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently; a third promoter (gamma) was identified for this gene in the 3' region. The RefSeq project has decided to create only a few representative transcript variants of the multitude that are possible. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2.
Gene Details:
neurexin 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human NRXN1
Molecular Weight:
43 kDa
Protein Details:
neurexin-1
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody