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Antibodies

GSTA2 Antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP78164-P050-25UL
100 ul
£412.00
ARP78164-P050-100UL
About this Product
SKU:
ARP78164-P050
Additional Names:
GST2; GTA2; GTH2; GSTA2-2
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds; including carcinogens; therapeutic drugs; environmental toxins and products of oxidative stress; by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present; eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha; kappa; mu; omega; pi; sigma; theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes; located in a cluster mapped to chromosome 6; are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver; the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
Gene Details:
glutathione S-transferase alpha 2
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human GSTA2
Molecular Weight:
26 kDa
Protein Details:
glutathione S-transferase A2
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody