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Antibodies

EPHB2 Antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP78020-P050-25UL
100 ul
£412.00
ARP78020-P050-100UL
About this Product
SKU:
ARP78020-P050
Additional Names:
DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5; BDPLT22
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain; a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility; division; and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade; resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants.
Gene Details:
EPH receptor B2
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human EPHB2
Molecular Weight:
116 kDa
Protein Details:
ephrin type-B receptor 2
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody