GSTA3 Antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP76238-P050-25UL
100 ul
£412.00
ARP76238-P050-100UL
About this Product
- SKU:
- ARP76238-P050
- Additional Names:
- GTA3; GSTA3-3
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic; carcinogenic; and pharmacologically active electrophilic compounds. At present; eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha; kappa; mu; omega; pi; sigma; theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However; during evolution; this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified; but its full length sequence has not been determined.
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human GSTA3
- Molecular Weight:
- 25kDa
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
