RASH Antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP74951-P050-25UL
100 ul
£412.00
ARP74951-P050-100UL
About this Product
- SKU:
- ARP74951-P050
- Additional Names:
- CTLO; HAMSV; HRAS1; RASH1; p21ras; C-H-RAS; H-RASIDX; C-BAS/HAS; C-HA-RAS1
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene belongs to the Ras oncogene family; whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP; and they have intrinsic GTPase activity. This protein undergoes a continuous cycle of de- and re-palmitoylation; which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome; a disease characterized by increased growth at the prenatal stage; growth deficiency at the postnatal stage; predisposition to tumor formation; cognitive disability; skin and musculoskeletal abnormalities; distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers; including bladder cancer; follicular thyroid cancer; and oral squamous cell carcinoma. Multiple transcript variants; which encode different isoforms; have been identified for this gene.
- Gene Details:
- HRas proto-oncogene; GTPase
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human RASH
- Molecular Weight:
- 20kDa
- Protein Details:
- GTPase HRas
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
