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Antibodies

4EBP1 Antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP74511-P050-25UL
100 ul
£412.00
ARP74511-P050-100UL
About this Product
SKU:
ARP74511-P050
Additional Names:
BP-1; 4EBP1; 4E-BP1; PHAS-I
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E); which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling; resulting in its dissociation from eIF4E and activation of mRNA translation.
Gene Details:
eukaryotic translation initiation factor 4E binding protein 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Human 4EBP1
Molecular Weight:
12kDa
Protein Details:
eukaryotic translation initiation factor 4E-binding protein 1
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody