ATP6V1B1 Antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP74408-P050-25UL
100 ul
£412.00
ARP74408-P050-100UL
About this Product
- SKU:
- ARP74408-P050
- Additional Names:
- VATB; VMA2; VPP3; DRTA2; RTA1B; ATP6B1
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes a component of vacuolar ATPase (V-ATPase); a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting; zymogen activation; receptor-mediated endocytosis; and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits; two G subunits plus the C; D; E; F; and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a; c; c'; c''; and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness.
- Gene Details:
- ATPase; H+ transporting; lysosomal 56/58kDa; V1 subunit B1
- Host:
- Rabbit
- Immunogen:
- The immunogen for Anti-ATP6V1B1 antibody is: synthetic peptide directed towards the N-terminal region of Human VATB1
- Molecular Weight:
- 56 kDa
- Purification:
- Affinity purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
