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Antibodies

ATF2 Antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP74400-P050-25UL
100 ul
£412.00
ARP74400-P050-100UL
About this Product
SKU:
ARP74400-P050
Additional Names:
HB16; CREB2; TREB7; CREB-2; CRE-BP1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE); an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene.
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C-terminal region of Human ATF2
Molecular Weight:
53kDa
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody