APLP2 Antibody - middle region
Product Sizes
25ul
£177.00
ARP73748-P050-25UL
100 ul
£412.00
ARP73748-P050-100UL
About this Product
- SKU:
- ARP73748-P050
- Additional Names:
- APPH; APPL2; CDEBP; APLP-2
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes amyloid precursor- like protein 2 (APLP2); which is a member of the APP (amyloid precursor protein) family including APP; APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-; copper- and zinc- binding domains at the N-terminus; BPTI/Kunitz inhibitor and E2 domains in the middle region; and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission; spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of Human APLP2
- Molecular Weight:
- 83kDa
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
