BCR Antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP72510-P050-25UL
100 ul
£412.00
ARP72510-P050-100UL
About this Product
- SKU:
- ARP72510-P050
- Additional Names:
- ALL; CML; PHL; BCR1; D22S11; D22S662
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome; which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL; the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied; the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- breakpoint cluster region
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of human BCR
- Molecular Weight:
- 34kDa
- Protein Details:
- breakpoint cluster region protein
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
