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Antibodies

GRAP Antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP70503-P050-25UL
100 ul
£412.00
ARP70503-P050-100UL
About this Product
SKU:
ARP70503-P050
Additional Names:
DFNB114
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin; and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general; it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N-terminal region of Human GRAP
Molecular Weight:
25kDa
Protein Details:
GRB2-related adapter protein
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody