DAND5 Antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP66787-P050-25UL
100 ul
£412.00
ARP66787-P050-100UL
About this Product
- SKU:
- ARP66787-P050
- Additional Names:
- SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs; BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists; to which this gene belongs; is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP; this gene may play a role in regulating organogenesis; body patterning; and tissue differentiation. In mouse; this protein has been shown to bind Nodal and to inhibit the Nodal signaling pathway which patterns left/right body asymmetry.
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human DAND5
- Molecular Weight:
- 21kDa
- Protein Details:
- DAN domain family member 5
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
