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Antibodies

COQ6 Antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP64161-P050-25UL
100 ul
£412.00
ARP64161-P050-100UL
About this Product
SKU:
ARP64161-P050
Additional Names:
CGI10; CGI-10; COQ10D6
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone); which is an essential component of the mitochondrial electron transport chain; and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6); which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N-terminal region of Human COQ6
Molecular Weight:
48kDa
Protein Details:
Ubiquinone biosynthesis monooxygenase COQ6
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody