LILRB2 antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP63917-P050-25UL
100 ul
£412.00
ARP63917-P050-100UL
About this Product
- SKU:
- ARP63917-P050
- Additional Names:
- ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family; which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains; a transmembrane domain; and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- Leukocyte immunoglobulin-like receptor; subfamily B (with TM and ITIM domains); member 2
- Host:
- Rabbit
- Molecular Weight:
- 65 kDa
- Protein Details:
- Leukocyte immunoglobulin-like receptor subfamily B member 2
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
