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Antibodies

TNFSF8 antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP63790-P050-25UL
100 ul
£412.00
ARP63790-P050-100UL
About this Product
SKU:
ARP63790-P050
Additional Names:
CD153; CD30L; CD30LG; TNLG3A
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30; which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines; while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.
Gene Details:
Tumor necrosis factor (ligand) superfamily; member 8
Host:
Rabbit
Molecular Weight:
26kDa
Protein Details:
Tumor necrosis factor ligand superfamily member 8
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody