SLC7A5 antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP63651-P050-25UL
100 ul
£412.00
ARP63651-P050-100UL
About this Product
- SKU:
- ARP63651-P050
- Additional Names:
- E16; CD98; LAT1; 4F2LC; MPE16; D16S469E
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- SLC7A5 is a sodium-independent; high-affinity transport of large neutral amino acids such as phenylalanine; tyrosine; leucine; arginine and tryptophan; when associated with SLC3A2/4F2hc. SLC7A5 is involved in cellular amino acid uptake. SLC7A5 acts as an amino acid exchanger. SLC7A5 is involved in the transport of L-DOPA across the blood-brain barrier; and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. SLC7A5 plays a role in neuronal cell proliferation (neurogenesis) in brain. SLC7A5 is involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D;L-homocysteine complexes; and hence plays a role in metal ion homeostasis and toxicity. SLC7A5 is involved in the cellular activity of small molecular weight nitrosothiols; via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. SLC7A5 may play an important role in high-grade gliomas. SLC7A5 mediates blood-to-retina L-leucine transport across the inner blood-retinal barrier which in turn may play a key role in maintaining large neutral amino acids as well as neurotransmitters in the neural retina. SLC7A5 acts as the major transporter of tyrosine in fibroblasts.
- Gene Details:
- Solute carrier family 7 (amino acid transporter light chain; L system); member 5
- Host:
- Rabbit
- Molecular Weight:
- 56kDa
- Protein Details:
- Large neutral amino acids transporter small subunit 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
