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Antibodies

SOST Antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP63543-P050-25UL
100 ul
£412.00
ARP63543-P050-100UL
About this Product
SKU:
ARP63543-P050
Additional Names:
CDD; VBCH; DAND6; SOST1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder; sclerosteosis; which causes progressive bone overgrowth. A deletion downstream of this gene; which causes reduced sclerostin expression; is associated with a milder form of the disorder called van Buchem disease.
Gene Details:
sclerostin
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the C terminal region of human SOST
Molecular Weight:
23 kDa
Protein Details:
Sclerostin
Purification:
Affinity purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody