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Antibodies

FPGT antibody - C-terminal region

Product Sizes
25ul
£177.00
ARP62823-P050-25UL
100 ul
£412.00
ARP62823-P050-100UL
About this Product
SKU:
ARP62823-P050
Additional Names:
GFPP
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules; such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose; the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues; such as liver and kidney; and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate; and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream TNNI3 interacting kinase (TNNI3K) gene.
Gene Details:
Fucose-1-phosphate guanylyltransferase
Host:
Rabbit
Molecular Weight:
37kDa
Protein Details:
Fucose-1-phosphate guanylyltransferase Ensembl ENSP00000432819
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody