HLA-DMA antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP61256-P050-25UL
100 ul
£412.00
ARP61256-P050-100UL
About this Product
- SKU:
- ARP61256-P050
- Additional Names:
- DMA; HLADM; RING6; D6S222E
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB); both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes; dendritic cells; macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain and the cytoplasmic tail.
- Gene Details:
- Major histocompatibility complex; class II; DM alpha
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human HLA-DMA
- Molecular Weight:
- 29kDa
- Protein Details:
- DMA protein EMBL CAA60781.1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
