H3f3a antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP60983-P050-25UL
100 ul
£412.00
ARP60983-P050-100UL
About this Product
- SKU:
- ARP60983-P050
- Additional Names:
- H3-3; H3.3; H3-3a; H3-3b; H3.3A; EyeLinc14
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- H3f3a is a variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. H3f3a constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. H3f3a is deposited at sites of nucleosomal displacement throughout transcribed genes; suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin; limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation; DNA repair; DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones; also called histone code; and nucleosome remodeling.
- Gene Details:
- H3 histone; family 3A
- Host:
- Rabbit
- Molecular Weight:
- 15kDa
- Protein Details:
- Histone H3.3
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
