BTBD12 antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP59857-P050-25UL
100 ul
£412.00
ARP59857-P050-100UL
About this Product
- SKU:
- ARP59857-P050
- Additional Names:
- FANCP; BTBD12; MUS312
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1; MUS81-EME1; and SLX1 endonucleases; and also associates with MSH2/MSH3 mismatch repair complex; telomere binding complex TERF2(TRF2)-TERF2IP(RAP1); the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.
- Gene Details:
- SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human BTBD12
- Molecular Weight:
- 200kDa
- Protein Details:
- Structure-specific endonuclease subunit SLX4
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
