Arhgef4 Antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP59254-P050-25UL
100 ul
£412.00
ARP59254-P050-100UL
About this Product
- SKU:
- ARP59254-P050
- Additional Names:
- As; Asef; 9330140K16Rik; C230030N03Rik
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Arhgef4 acts as guanine nucleotide exchange factor (GEF) for RHOA; RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion By similarity. It is required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Arhgef4 is involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
- Gene Details:
- Rho guanine nucleotide exchange factor (GEF) 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Arhgef4
- Molecular Weight:
- 57kDa
- Protein Details:
- Rho guanine nucleotide exchange factor 4
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
