IL7R antibody - middle region
Product Sizes
25ul
£177.00
ARP59084-P050-25UL
100 ul
£412.00
ARP59084-P050-100UL
About this Product
- SKU:
- ARP59084-P050
- Additional Names:
- ILRA; CD127; IL7RA; CDW127; IL-7R-alpha
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor; gamma chain (IL2RG); which is a common gamma chain shared by the receptors of various cytokines; including interleukine 2; 4; 7; 9; and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID).
- Gene Details:
- Interleukin 7 receptor
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human IL7R
- Molecular Weight:
- 49kDa
- Protein Details:
- Interleukin-7 receptor subunit alpha
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
