TLR4 antibody - middle region
Product Sizes
25ul
£177.00
ARP59041-P050-25UL
100 ul
£412.00
ARP59041-P050-100UL
About this Product
- SKU:
- ARP59041-P050
- Additional Names:
- TOLL; CD284; TLR-4; ARMD10
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents; and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta; and in myelomonocytic subpopulation of the leukocytes. It has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Also; several transcript variants of this gene have been found; but the protein coding potential of most of them is uncertain.
- Gene Details:
- Toll-like receptor 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human TLR4
- Molecular Weight:
- 93kDa
- Protein Details:
- Toll-like receptor 4
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
