ATP6V1C1 antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP58589-P050-25UL
100 ul
£412.00
ARP58589-P050-100UL
About this Product
- SKU:
- ARP58589-P050
- Additional Names:
- VATC; Vma5; ATP6C; ATP6D
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- ATP6V1C1 is a component of vacuolar ATPase (V-ATPase); a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting; zymogen activation; receptor-mediated endocytosis; and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits; two G subunits plus the C; D; E; F; and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a; c; c'; c''; and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously; this gene was designated ATP6D.This gene encodes a component of vacuolar ATPase (V-ATPase); a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting; zymogen activation; receptor-mediated endocytosis; and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits; two G subunits plus the C; D; E; F; and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a; c; c'; c''; and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously; this gene was designated ATP6D. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Gene Details:
- ATPase; H+ transporting; lysosomal 42kDa; V1 subunit C1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human ATP6V1C1
- Molecular Weight:
- 42kDa
- Protein Details:
- V-type proton ATPase subunit C 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
