RUNX1T1 antibody - middle region
Product Sizes
25ul
£177.00
ARP58127-P050-25UL
100 ul
£412.00
ARP58127-P050-100UL
About this Product
- SKU:
- ARP58127-P050
- Additional Names:
- CDR; ETO; MTG8; AML1T1; ZMYND2; CBFA2T1; AML1-MTG8
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- RUNX1T1 is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia; especially in the M2 subtype; the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. The protein encoded by this gene is a putative zinc finger transcription factor and oncoprotein. In acute myeloid leukemia; especially in the M2 subtype; the t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities. The translocation produces a chimeric gene made up of the 5'-region of the RUNX1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Several transcript variants encoding multiple isoforms have been found for this gene.
- Gene Details:
- Runt-related transcription factor 1; translocated to; 1 (cyclin D-related)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human RUNX1T1
- Molecular Weight:
- 64kDa
- Protein Details:
- cDNA; FLJ92968; highly similar to Homo sapiens runt-related transcription factor 1; translocated to; 1 (cyclin D-related) (RUNX1T1); transcript variant 1; mRNA EMBL BAG35486.1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
