ALS2 Antibody - middle region
Product Sizes
25ul
£177.00
ARP57487-P050-25UL
About this Product
- SKU:
- ARP57487-P050
- Additional Names:
- ALSJ; PLSJ; IAHSP; ALS2CR6
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene contains an ATS1/RCC1-like domain; a RhoGEF domain; and a vacuolar protein sorting 9 (VPS9) domain; all of which are guanine-nucleotide exchange factors that activate members of the Ras superfamily of GTPases. The protein functions as a guanine nucleotide exchange factor for the small GTPase RAB5. The protein localizes with RAB5 on early endosomal compartments; and functions as a modulator for endosomal dynamics. Mutations in this gene result in several forms of juvenile lateral sclerosis and infantile-onset ascending spastic paralysis. Multiple transcript variants encoding different isoforms have been found for this gene.
- Gene Details:
- Amyotrophic lateral sclerosis 2 (juvenile)
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human ALS2
- Molecular Weight:
- 184kDa
- Protein Details:
- Alsin
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
