CALCOCO1 antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP57483-P050-25UL
100 ul
£412.00
ARP57483-P050-100UL
About this Product
- SKU:
- ARP57483-P050
- Additional Names:
- Cocoa; PP13275; calphoglin
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- CALCOCO1 functions as a coactivator for aryl hydrocarbon and nuclear receptors (NR).CALCOCO1 is recruited to promoters through its contact with the N-terminal basic helix-loop-helix-Per-Arnt-Sim (PAS) domain of transcription factors or coactivators; such as NCOA2. During ER-activation CALCOCO1 acts synergistically in combination with other NCOA2-binding proteins; such as EP300; CREBBP and CARM1. CALCOCO1 is involved in the transcriptional activation of target genes in the Wnt/CTNNB1 pathway. CALCOCO1 functions as a secondary coactivator in LEF1-mediated transcriptional activation via its interaction with CTNNB1. Coactivator function for nuclear receptors and LEF1/CTNNB1 involves differential utilization of two different activation regions.
- Gene Details:
- Calcium binding and coiled-coil domain 1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human CALCOCO1
- Molecular Weight:
- 77kDa
- Protein Details:
- Calcium-binding and coiled-coil domain-containing protein 1
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
