ALDH18A1 antibody - N-terminal region
Product Sizes
25ul
£177.00
ARP56216-P050-25UL
100 ul
£412.00
ARP56216-P050-100UL
About this Product
- SKU:
- ARP56216-P050
- Additional Names:
- GSAS; P5CS; PYCS; SPG9; ADCL3; SPG9A; SPG9B; ARCL3A
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate; a critical step in the de novo biosynthesis of proline; ornithine and arginine. Mutations in this gene lead to hyperammonemia; hypoornithinemia; hypocitrullinemia; hypoargininemia and hypoprolinemia and may be associated with neurodegeneration; cataracts and connective tissue diseases.This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate; a critical step in the de novo biosynthesis of proline; ornithine and arginine. Mutations in this gene lead to hyperammonemia; hypoornithinemia; hypocitrullinemia; hypoargininemia and hypoprolinemia and may be associated with neurodegeneration; cataracts and connective tissue diseases. Alternatively spliced transcript variants; encoding different isoforms; have been described for this gene.
- Gene Details:
- Aldehyde dehydrogenase 18 family; member A1
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the N terminal region of human ALDH18A1
- Molecular Weight:
- 87 kDa
- Protein Details:
- Delta-1-pyrroline-5-carboxylate synthase
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
