BLMH antibody - middle region
Product Sizes
25ul
£177.00
ARP56106-P050-25UL
100 ul
£412.00
ARP56106-P050-100UL
About this Product
- SKU:
- ARP56106-P050
- Additional Names:
- BH; BMH
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The normal physiological role of BLM hydrolase is unknown; but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity.Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however; the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM); an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
- Gene Details:
- Bleomycin hydrolase
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human BLMH
- Molecular Weight:
- 52kDa
- Protein Details:
- Bleomycin hydrolase
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
