IL4 antibody - middle region
Product Sizes
25ul
£177.00
ARP54330-P050-25UL
100 ul
£412.00
ARP54330-P050-100UL
About this Product
- SKU:
- ARP54330-P050
- Additional Names:
- BSF1; IL-4; BCGF1; BSF-1; BCGF-1
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- IL4 participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13; which may contribute to many overlapping functions of this cytokine and IL13. STAT6; a signal transducer and activator of transcription; has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene; IL3; IL5; IL13; and CSF2 form a cytokine gene cluster on chromosome 5q; with this gene particularly close to IL13. This gene; IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- Gene Details:
- Interleukin 4
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human IL4
- Molecular Weight:
- 15kDa
- Protein Details:
- Interleukin-4
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
