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Antibodies

APOE antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP54284-P050-25UL
100 ul
£412.00
ARP54284-P050-100UL
About this Product
SKU:
ARP54284-P050
Additional Names:
AD2; LPG; APO-E; ApoE4; LDLCQ5
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E; a main apoprotein of the chylomicron; binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia; or type III hyperlipoproteinemia (HLP III); in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Gene Details:
Apolipoprotein E
Host:
Rabbit
Molecular Weight:
36 kDa
Protein Details:
Apolipoprotein E
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody