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Antibodies

PRDX3 antibody - N-terminal region

Product Sizes
25ul
£177.00
ARP52341-P050-25UL
100 ul
£412.00
ARP52341-P050-100UL
About this Product
SKU:
ARP52341-P050
Additional Names:
AOP1; MER5; AOP-1; SP-22; HBC189; PRO1748; prx-III
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
PRDX3 is a protein with antioxidant function and is localized in the mitochondrion. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved; and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation; differentiation; and antioxidant functions. This gene encodes a protein with antioxidant function and is localized in the mitochondrion. This gene shows significant nucleotide sequence similarity to the gene coding for the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase. Expression of this gene product in E. coli deficient in the C22-subunit gene rescued resistance of the bacteria to alkylhydroperoxide. The human and mouse genes are highly conserved; and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologues suggest that these genes consist of a family that is responsible for regulation of cellular proliferation; differentiation; and antioxidant functions. Two transcript variants encoding two different isoforms have been found for this gene.
Gene Details:
Peroxiredoxin 3
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX3
Molecular Weight:
26kDa
Protein Details:
Thioredoxin-dependent peroxide reductase; mitochondrial
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody