ABAT antibody - middle region
Product Sizes
25ul
£177.00
ARP51765-P050-25UL
100 ul
£412.00
ARP51765-P050-100UL
About this Product
- SKU:
- ARP51765-P050
- Additional Names:
- GABAT; NPD009; GABA-AT
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA); an important; mostly inhibitory neurotransmitter in the central nervous system; into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation; hypotonia; hyperreflexia; lethargy; refractory seizures; and EEG abnormalities. 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA); an important; mostly inhibitory neurotransmitter in the central nervous system; into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation; hypotonia; hyperreflexia; lethargy; refractory seizures; and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
- Gene Details:
- 4-aminobutyrate aminotransferase
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human ABAT
- Molecular Weight:
- 56kDa
- Protein Details:
- 4-aminobutyrate aminotransferase; mitochondrial
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
