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Antibodies

HLA-DPA1 antibody - middle region

Product Sizes
25ul
£177.00
ARP50199-P050-25UL
100 ul
£412.00
ARP50199-P050-100UL
About this Product
SKU:
ARP50199-P050
Additional Names:
DPA1; PLT1; HLADP; HLASB; DP(W3); DP(W4); HLA-DPA; HLA-DP1A; HLA-DPB1
Clonality:
Polyclonal
Concentration:
0.5 mg/ml
Extra Details:
The specific function of this protein remains unknown.HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain; both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes; dendritic cells; macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide; exons 2 and 3 encode the two extracellular domains; exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities; resulting in up to 4 different molecules. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Gene Details:
Major histocompatibility complex; class II; DP alpha 1
Host:
Rabbit
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human HLA-DPA1
Molecular Weight:
26kDa
Protein Details:
HLA class II histocompatibility antigen; DP alpha 1 chain
Purification:
Affinity Purified
Shipping Conditions:
Blue Ice
Storage Conditions:
For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
Supplier:
Aviva Systems Biology
Type:
Antibodies: Polyclonal Antibody