SIGLEC10 antibody - middle region
Product Sizes
25ul
£177.00
ARP50160-P050-25UL
100 ul
£412.00
ARP50160-P050-100UL
About this Product
- SKU:
- ARP50160-P050
- Additional Names:
- SLG2; PRO940; SIGLEC-10
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. SIGLEC10 preferentially binds to alpha-2;3- or alpha-2;6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response; SIGLEC10 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.SIGLECs are members of the immunoglobulin superfamily that are expressed on the cell surface. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs; or ITIMs. SIGLECs are typically expressed on cells of the innate immune system; with the exception of the B-cell expressed SIGLEC6 (MIM 604405).[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-653 AC008750.9 90495-91147 c 654-760 DA387605.1 391-497 761-2959 AF301007.1 262-2460 2960-3794 AY358337.1 1930-2764
- Gene Details:
- Sialic acid binding Ig-like lectin 10
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the middle region of human SIGLEC10
- Molecular Weight:
- 76kDa
- Protein Details:
- Sialic acid-binding Ig-like lectin 10
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
