ATRX Antibody - C-terminal region
Product Sizes
25ul
£177.00
ARP47775-P050-25UL
100 ul
£412.00
ARP47775-P050-100UL
About this Product
- SKU:
- ARP47775-P050
- Additional Names:
- JMS; XH2; XNP; MRX52; RAD54; RAD54L; ZNF-HX
- Clonality:
- Polyclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- The protein encoded by this gene contains an ATPase/helicase domain; and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. The mutations of this gene are associated with an X-linked mental retardation (XLMR) syndrome most often accompanied by alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation; which may provide a link between chromatin remodeling; DNA methylation; and gene expression in developmental processes. This protein is found to undergo cell cycle-dependent phosphorylation; which regulates its nuclear matrix and chromatin association; and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported.
- Gene Details:
- similar to putative DNA dependent ATPase and helicase
- Host:
- Rabbit
- Immunogen:
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ATRX
- Molecular Weight:
- 148kDa
- Protein Details:
- Transcriptional regulator ATRX
- Purification:
- Affinity Purified
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- For short term use; store at 2-8C up to 1 week. For long term storage; store at -20C in small aliquots to prevent freeze-thaw cycles.
- Supplier:
- Aviva Systems Biology
- Type:
- Antibodies: Polyclonal Antibody
- Manufacturer's Data Sheet:html_datasheet.php
